ABT 751

Name ABT 751
Supplier Tocris Bioscience
Catalog 2214
Prices $209.00, $879.00
Sizes 10 mg, 50 mg
Cas Number 141430-65-1
Chemical Name N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide
Formula C18H17N3O4S
Molecular Weight 371.41
Purity >98 %
Description Antimitotic agent, inhibits microtubule polymerization. Binds to β -tubulin on the colchine site; blocks cell cycle at G 2 M phase and induces apoptosis. Exhibits antitumor activity. Also displays activity in cell lines resistant to vincristine, doxorubicin and cisplatin. Orally bioavailable.
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