AC 261066

• Supplier: Tocris Bioscience
• Catalog: 3419
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 870773-76-5
• Chemical Name: 4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoicacid
• Formula: C17H20FNO4S
• Molecular Weight: 353.41
• Purity: >98 %
• Description: Potent RAR β 2 agonist (pEC 50 = 8.1). Selective over RAR β 1, RAR α and RAR γ (pEC 50 values are 6.4, 6.2 and 6.3 respectively). More potent and orally available than AC 55649 (Cat. No. 2436).

Product References

Discovery of a potent, orally available, and isoform-selective retinoic acid - Discovery of a potent, orally available, and isoform-selective retinoic acid

Lund BW, Piu F, Gauthier NK, Eeg A, Currier E, Sherbukhin V, Brann MR, Hacksell U, Olsson R. J Med Chem. 2005 Dec 1;48(24):7517-9.

Design, synthesis, and structure-activity analysis of isoform-selective retinoic - Design, synthesis, and structure-activity analysis of isoform-selective retinoic

Lund BW, Knapp AE, Piu F, Gauthier NK, Begtrup M, Hacksell U, Olsson R. J Med Chem. 2009 Mar 26;52(6):1540-5.