| Name | AC 5216 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3043 |
| Prices | $165.00, $685.00 |
| Sizes | 10 mg, 50 mg |
| Cas Number | 226954-04-7 |
| Chemical Name | N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide |
| Formula | C23H23N5O2 |
| Molecular Weight | 401.46 |
| Purity | >98 % |
| Description | Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (K i = 0.297 nM), and high potency against human and rat glial TSPO (IC 50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects. |
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