AC 55649

• Supplier: Tocris Bioscience
• Catalog: 3369
• Prices: $129.00, $535.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 59662-49-6
• Chemical Name: 4'-Octyl-[1,1'-biphenyl]-4-carboxylicacid
• Formula: C21H26O2
• Molecular Weight: 310.44
• Purity: >99 %
• Description: Potent, isoform-selective RAR β 2 receptor agonist (pEC 50 values are 6.9, 5.7 and 5.6 at RAR β 2, RAR β 1 and RAR α respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.

Product References

Discovery of a potent, orally available, and isoform-selective retinoic acid - Discovery of a potent, orally available, and isoform-selective retinoic acid

Lund BW, Piu F, Gauthier NK, Eeg A, Currier E, Sherbukhin V, Brann MR, Hacksell U, Olsson R. J Med Chem. 2005 Dec 1;48(24):7517-9.

Design, synthesis, and structure-activity analysis of isoform-selective retinoic - Design, synthesis, and structure-activity analysis of isoform-selective retinoic

Lund BW, Knapp AE, Piu F, Gauthier NK, Begtrup M, Hacksell U, Olsson R. J Med Chem. 2009 Mar 26;52(6):1540-5.