(±)-AC 7954 hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 5013
• Prices: $189.00, $765.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 477313-09-0
• Chemical Name: (±)-3-(4-Chlorophenyl)-3-[2-(dimethylamino)ethyl]-3,4-dihydro-1H-2-benzopyran-1-onehydrochloride
• Formula: C19H20ClNO2.HCl
• Molecular Weight: 366.28
• Purity: >98 %
• Description: Highly selective, non-peptide urotensin-II (UT) receptor agonist that displays potent activity at human and rat UT receptors (pEC 50 values are 6.5 and 6.7 respectively).

Product References

Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: - Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor:

Croston GE, Olsson R, Currier EA, Burstein ES, Weiner D, Nash N, Severance D, Allenmark SG, Thunberg L, Ma JN, Mohell N, O'Dowd B, Brann MR, Hacksell U. J Med Chem. 2002 Nov 7;45(23):4950-3.

Architecture of the human urotensin II receptor: comparison of the binding - Architecture of the human urotensin II receptor: comparison of the binding

Lavecchia A, Cosconati S, Novellino E. J Med Chem. 2005 Apr 7;48(7):2480-92.

Novel potent and efficacious nonpeptidic urotensin II receptor agonists. - Novel potent and efficacious nonpeptidic urotensin II receptor agonists.

Lehmann F, Pettersen A, Currier EA, Sherbukhin V, Olsson R, Hacksell U, Luthman K. J Med Chem. 2006 Apr 6;49(7):2232-40.