Acarbose

• Supplier: Tocris Bioscience
• Catalog: 5540
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 56180-94-0
• Chemical Name: O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glucose
• Formula: C25H43NO18
• Molecular Weight: 645.25
• Description: Inhibitor of intestinal α -glucosidase (IC 50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates.

Product References

Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase - Inhibition of disaccharide digestion in rat intestine by the alpha-glucosidase

Krause HP, Keup U, Puls W. Digestion. 1982;23(4):232-8.

Acarbose. An update of its pharmacology and therapeutic use in diabetes mellitus. - Acarbose. An update of its pharmacology and therapeutic use in diabetes mellitus.

Balfour JA, McTavish D. Drugs. 1993 Dec;46(6):1025-54.

Evaluation of alpha-glucosidase inhibition by using an immobilized assay system. - Evaluation of alpha-glucosidase inhibition by using an immobilized assay system.

Oki T, Matsui T, Matsumoto K. Biol Pharm Bull. 2000 Sep;23(9):1084-7.