N -Acetyl- O -phosphono-Tyr-Glu-Glu-Ile-Glu

• Supplier: Tocris Bioscience
• Catalog: 1930
• Prices: $99.00
• Sizes: 1 mg
• Cas Number: 159439-02-8
• Chemical Name: N-Acetyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl]-L-α-glutamyl-L-isoleucyl]-L-glutamicacid
• Formula: C32H46N5O17P
• Molecular Weight: 803.71
• Description: Phosphopeptide ligand for the src SH2 domain (IC 50 = 1 μ M). Blocks src interactions with EGFR and FAK.

Product References

Peptide inhibitors of src SH3-SH2-phosphoprotein interactions. - Peptide inhibitors of src SH3-SH2-phosphoprotein interactions.

Gilmer T, Rodriguez M, Jordan S, Crosby R, Alligood K, Green M, Kimery M, Wagner C, Kinder D, Charifson P, et al.. J Biol Chem. 1994 Dec 16;269(50):31711-9.

Potent dipeptide inhibitors of the pp60c-src SH2 domain. - Potent dipeptide inhibitors of the pp60c-src SH2 domain.

Pacofsky GJ, Lackey K, Alligood KJ, Berman J, Charifson PS, Crosby RM, Dorsey GF Jr, Feldman PL, Gilmer TM, Hummel CW, Jordan SR, Mohr C, Shewchuk LM, Sternbach DD, Rodriguez M. J Med Chem. 1998 May 21;41(11):1894-908.

Design and characterization of non-phosphopeptide inhibitors for Src family SH2 - Design and characterization of non-phosphopeptide inhibitors for Src family SH2

Park SH, Won J, Lee KH. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2711-4.