| Name | ACHP |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 0357 |
| Prices | $265.00 |
| Sizes | 10 mg |
| Function Type | Inhibitor |
| Cas Number | 406208-42-2 |
| Chemical Name | 2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile |
| Formula | C21H24N4O2 |
| Molecular Weight | 364.44 |
| Purity | >97 % |
| Description | I κ B kinase inhibitor (IC 50 values are 8.5 and 250 nM for IKK β and IKK α respectively). Selective for IKK α and IKK β over IKK3, Syk and MAPKKK4 (IC 50 values are > 20 μ M). Inhibits DNA binding activity of NF- κ B. Blocks NF- κ B pathway in multiple myeloma cell lines; induces cell growth arrest and apoptosis. |
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