(1 S ,3 R )-ACPD

• Supplier: Tocris Bioscience
• Catalog: 1781
• Prices: $249.00, $1,025.00
• Sizes: 10 mg, 50 mg
• Cas Number: 111900-32-4
• Chemical Name: (1S,3R)-1-Aminocyclopentane-1,3-dicarboxylicacid
• Formula: C7H11NO4
• Molecular Weight: 173.17
• Purity: >98 %
• Description: Active isomer of (±)- trans -ACPD (Cat. No. 0187). Agonist at both group I and II mGlu receptors (EC 50 values are 5, 15, 42 and 60 μ M at mGluR 2 , mGluR 5 , mGluR 1 and mGluR 6 respectively). NPEC-caged-(1 S ,3 R )-ACPD also available (Cat. No. 3331). (±)- trans -ACPD (Cat. No. 0187) and cis -ACPD (Cat. No. 0186) also available.

Product References

Metabotropic glutamate receptors: novel targets for drug development. - Metabotropic glutamate receptors: novel targets for drug development.

Knopfel T, Kuhn R, Allgeier H. J Med Chem. 1995 Apr 28;38(9):1417-26.

Differences in agonist and antagonist activities for two indices of metabotropic - Differences in agonist and antagonist activities for two indices of metabotropic

Mistry R, Challiss RA. Br J Pharmacol. 1996 Apr;117(8):1735-43.

Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues - Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues

Conti P, De Amici M, Brauner-Osborne H, Madsen U, Toma L, De Micheli C. Farmaco. 2002 Nov;57(11):889-95.