cis -ACPD

• Supplier: Tocris Bioscience
• Catalog: 0284
• Prices: $175.00, $709.00
• Sizes: 10 mg, 50 mg
• Function Type: Agonist
• Cas Number: 477331-06-9
• Chemical Name: (±)-1-Aminocyclopentane-cis-1,3-dicarboxylicacid
• Formula: C7H11NO4
• Molecular Weight: 173.17
• Description: 1:1 mixture of (1 R ,3 R )- and (1 S ,3 S )-ACPD. Potent NMDA receptor agonist and selective group II mGluR agonist (EC 50 values are 13, 50, >300 and >300 μ M at mGluR 2 , mGluR 4 , mGluR 1 and mGluR 5 respectively). Exhibits proconvulsant activity in vivo . (±)- trans -ACPD (Cat. No. 0187) and (1 S ,3 R )-ACPD (Cat. No. 0284) also available.

Product References

In vitro and in vivo pharmacology of trans- and - In vitro and in vivo pharmacology of trans- and

Schoepp DD, Johnson BG, Salhoff CR, McDonald JW, Johnston MV. J Neurochem. 1991 May;56(5):1789-96.

Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues - Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues

Conti P, De Amici M, Brauner-Osborne H, Madsen U, Toma L, De Micheli C. Farmaco. 2002 Nov;57(11):889-95.