ACTH (1-39)

Name ACTH (1-39)
Supplier Tocris Bioscience
Catalog 5319
Prices $339.00
Sizes 1 mg
Function Type Agonist
Cas Number 12279-41-3
Formula C207H308N56O58S
Molecular Weight 4541.1
Description Potent endogenous melanocortin receptor 2 (MC 2 ) agonist (EC 50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro .
Supplier Page Shop

Product References

Agonist and receptor binding properties of adrenocorticotropin peptides using the - Agonist and receptor binding properties of adrenocorticotropin peptides using the

Kapas S, Cammas FM, Hinson JP, Clark AJ. Endocrinology. 1996 Aug;137(8):3291-4.

Melanocortin crosstalk with adipose functions: ACTH directly induces insulin - Melanocortin crosstalk with adipose functions: ACTH directly induces insulin

Iwen KA, Senyaman O, Schwartz A, Drenckhan M, Meier B, Hadaschik D, Klein J. J Endocrinol. 2008 Mar;196(3):465-72.

Brain effects of melanocortins. - Brain effects of melanocortins.

Bertolini A, Tacchi R, Vergoni AV. Pharmacol Res. 2009 Jan;59(1):13-47.