Actinomycin D

• Supplier: Tocris Bioscience
• Catalog: 3492
• Prices: $139.00
• Sizes: 10 mg
• Cas Number: 50-76-0
• Chemical Name: 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
• Formula: C62H86N12O16
• Molecular Weight: 1255.43
• Purity: >98 %
• Description: Anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis.

Product References

A kinetic study on the mechanism of inhibition of RNA synthesis catalyzed by - A kinetic study on the mechanism of inhibition of RNA synthesis catalyzed by

Aktipis S, Panayotatos N. Biochim Biophys Acta. 1981 Oct 27;655(3):278-90.

Apoptosis induced by Actinomycin D, Camptothecin or Aphidicolin can occur in all - Apoptosis induced by Actinomycin D, Camptothecin or Aphidicolin can occur in all

Glynn JM, Cotter TG, Green DR. Biochem Soc Trans. 1992 Feb;20(1):84S.

The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse - The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse

Jeeninga RE, Huthoff HT, Gultyaev AP, Berkhout B. Nucleic Acids Res. 1998 Dec 1;26(23):5472-9.