Acyclovir

• Supplier: Tocris Bioscience
• Catalog: 3205
• Prices: $95.00
• Sizes: 50 mg
• Cas Number: 59277-89-3
• Chemical Name: 2-Amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one
• Formula: C8H11N5O3
• Molecular Weight: 225.21
• Purity: >99 %
• Description: Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC 50 values are 0.85 and 0.86 μ M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).

Product References

The role of a HSV thymidine kinase stimulating substance, scopadulciol, in - The role of a HSV thymidine kinase stimulating substance, scopadulciol, in

Hayashi K, Lee JB, Maitani Y, Toyooka N, Nemoto H, Hayashi T. J Gene Med. 2006 Aug;8(8):1056-67.

Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex - Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex

Suzuki M, Okuda T, Shiraki K. Antiviral Res. 2006 Nov;72(2):157-61. Epub 2006 May 30.