| Name | Adaptaquin |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3716 |
| Prices | $139.00, $585.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 385786-48-1 |
| Chemical Name | 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol |
| Formula | C21H16ClN3O2 |
| Molecular Weight | 377.82 |
| Purity | >97 % |
| Description | HIF-prolyl hydroxylase-2 (PHD2) inhibitor. Blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant. |
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