AG 1478 hydrochloride

Name AG 1478 hydrochloride
Supplier Tocris Bioscience
Catalog 2730
Prices $159.00, $665.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 170449-18-0
Chemical Name N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinaninehydrochloride
Formula C16H14ClN3O2.HCl
Molecular Weight 352.22
Purity >98 %
Description Potent and selective inhibitor of epidermal growth factor receptor kinase (IC 50 values 3 nM for EGFR and > 100 μ M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC 50 = 1 μ M).
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