Alprostadil

• Supplier: Tocris Bioscience
• Catalog: 2806
• Prices: $165.00, $685.00
• Sizes: 10 mg, 50 mg
• Cas Number: 745-65-3
• Chemical Name: (11α,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oicacid
• Formula: C20H34O5
• Molecular Weight: 354.49
• Purity: >98 %
• Description: Prostaglandin with some selectivity for EP 3 and EP 4 receptors (K i values are 1.1, 2.1, 36, 10 and 33 nM for mouse EP 3 , EP 4 , EP 1 , EP 2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo .

Product References

Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin - Specificity between the anti-aggregatory actions of prostacyclin, prostaglandin

Whittle BJ, Hamid S, Lidbury P, Rosam AC. Adv Exp Med Biol. 1985;192:109-25.

Prostaglandin E1: a review. - Prostaglandin E1: a review.

Kirtland SJ. Prostaglandins Leukot Essent Fatty Acids. 1988;32(3):165-74.

Ligand binding specificities of the eight types and subtypes of the mouse - Ligand binding specificities of the eight types and subtypes of the mouse

Kiriyama M, Ushikubi F, Kobayashi T, Hirata M, Sugimoto Y, Narumiya S. Br J Pharmacol. 1997 Sep;122(2):217-24.