AM 2394

• Supplier: Tocris Bioscience
• Catalog: 3381
• Prices: $195.00, $819.00
• Sizes: 10 mg, 50 mg
• Function Type: Activator
• Cas Number: 1442684-77-6
• Chemical Name: N-[6'-(2-Hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3'-bipyridin]-6-yl]-N'-methylurea
• Formula: C22H25N5O4
• Molecular Weight: 423.47
• Purity: >98 %
• Description: Potent glucokinase activator (EC 50 = 60 nM). Orally bioavailable. Reduces plasma glucose levels in an oral glucose tolerance test in ob/ob mice.

Product References

123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain - 123I-labeled AM251: a radioiodinated ligand which binds in vivo to mouse brain

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Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251 - Binding of the non-classical cannabinoid CP 55,940, and the diarylpyrazole AM251

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Structure-activity relationships of pyrazole derivatives as cannabinoid receptor - Structure-activity relationships of pyrazole derivatives as cannabinoid receptor

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Inverse agonism and neutral antagonism at cannabinoid CB1 receptors. - Inverse agonism and neutral antagonism at cannabinoid CB1 receptors.

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The orphan receptor GPR55 is a novel cannabinoid receptor. - The orphan receptor GPR55 is a novel cannabinoid receptor.

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