AMBMP hydrochloride

Name AMBMP hydrochloride
Supplier Tocris Bioscience
Catalog 0388
Prices $139.00, $585.00
Sizes 10 mg, 50 mg
Function Type Activator
Chemical Name N4-(1,3-Benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediaminehydrochloride
Formula C19H18N4O3.HCl
Molecular Weight 386.84
Purity >98 %
Description Wnt canonical signaling activator. Also inhibits tubulin polymerization. Suppresses TLR2/4/5-induced inflammatory response in human monocytes. Inhibits cell proliferation and induces cell cycle arrest in MDA-MB-231 breast cancer cells. Also decreases embryo to blastocyst development.
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Product References

Antioxidant function of ambroxol in mononuclear and polymorphonuclear cells in - Antioxidant function of ambroxol in mononuclear and polymorphonuclear cells in

Gillissen A, Bartling A, Schoen S, Schultze-Werninghaus G. Lung. 1997;175(4):235-42.

Ambroxol inhibits the release of histamine, leukotrienes and cytokines from human - Ambroxol inhibits the release of histamine, leukotrienes and cytokines from human

Gibbs BF, Schmutzler W, Vollrath IB, Brosthardt P, Braam U, Wolff HH, Zwadlo-Klarwasser G. Inflamm Res. 1999 Feb;48(2):86-93.

Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) - Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+)

Weiser T, Wilson N. Mol Pharmacol. 2002 Sep;62(3):433-8.