( S )-AMPA

• Supplier: Tocris Bioscience
• Catalog: 0169
• Prices: $115.00, $255.00, $1,045.00
• Sizes: 1 mg, 10 mg, 50 mg
• Cas Number: 83643-88-3
• Chemical Name: (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid
• Formula: C7H10N2O4
• Molecular Weight: 186.17
• Purity: >99 %
• Description: Active enantiomer of AMPA (EC 50 = 3.5 μ M). Also available as part of the AMPA Receptor Tocriset™ (Cat. No. 1822). NPEC-caged-( S )-AMPA (Cat. No. 3840), inactive enantiomer ( R )-AMPA (Cat. No. 0253) and racemate ( RS )-AMPA (Cat. No. 0169) are also available.

Product References

Enzymic resolution and binding to rat brain membranes of the glutamic acid - Enzymic resolution and binding to rat brain membranes of the glutamic acid

Hansen JJ, Lauridsen J, Nielsen E, Krogsgaard-Larsen P. J Med Chem. 1983 Jun;26(6):901-3.

Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity - Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity

Lauridsen J, Honore T, Krogsgaard-Larsen P. J Med Chem. 1985 May;28(5):668-72.

Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, - Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry,

Falch E, Brehm L, Mikkelsen I, Johansen TN, Skjaerbaek N, Nielsen B, Stensbol TB, Ebert B, Krogsgaard-Larsen P. J Med Chem. 1998 Jul 2;41(14):2513-23.