| Name | ANA 12 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 1429 |
| Prices | $189.00, $765.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Antagonist |
| Cas Number | 219766-25-3 |
| Chemical Name | N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide |
| Formula | C22H21N3O3S |
| Molecular Weight | 407.49 |
| Purity | >99 % |
| Description | TrkB receptor antagonist. Demonstrates a 2-site mode of action, preventing activation by BDNF non-competitively (IC 50 values are 45.6 nM and 41.1 μ M for the high and low affinity sites respectively). Displays no effect on TrkA and TrkC in an assay of neurite outgrowth. Demonstrates antidepressant properties. |
| Supplier Page | Shop |