(+)-Anabasine hydrochloride

• Supplier: Tocris Bioscience
• Catalog: 4781
• Prices: $105.00
• Sizes: 50 mg
• Function Type: Agonist
• Cas Number: 53912-89-3
• Chemical Name: (S)-(+)-3-(2-Piperidinyl)pyridinehydrochloride
• Formula: C10H14N2.HCl
• Molecular Weight: 198.69
• Purity: >99 %
• Description: High affinity neuronal nicotinic ACh receptor partial agonist (K i values are 0.058, 0.26 and 7.2 μ M for rat α 7, rat α 4 β 2 and fish skeletal muscle nAChRs respectively). Also stimulates Ca 2+ -dependent catecholamine release from rat adrenomedullary cells in vitro .

Product References

Anabaseine is a potent agonist on muscle and neuronal - Anabaseine is a potent agonist on muscle and neuronal

Kem WR, Mahnir VM, Papke RL, Lingle CJ. J Pharmacol Exp Ther. 1997 Dec;283(3):979-92.

Neuronal nicotinic receptor beta2 and beta4 subunits confer large differences in - Neuronal nicotinic receptor beta2 and beta4 subunits confer large differences in

Parker MJ, Beck A, Luetje CW. Mol Pharmacol. 1998 Dec;54(6):1132-9.

Desensitization of nicotinic agonist-induced [3H]gamma-aminobutyric acid release - Desensitization of nicotinic agonist-induced [3H]gamma-aminobutyric acid release

Lu Y, Marks MJ, Collins AC. J Pharmacol Exp Ther. 1999 Dec;291(3):1127-34.

Effect of anabasine on catecholamine secretion from the perfused rat adrenal - Effect of anabasine on catecholamine secretion from the perfused rat adrenal

Hong SP, Jeong MG, Lim DY. J Cardiol. 2007 Dec;50(6):351-62.