Anacardic acid

• Supplier: Tocris Bioscience
• Catalog: 1971
• Prices: $89.00, $375.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Cas Number: 16611-84-0
• Chemical Name: 2-Hydroxy-6-pentadecylbenzoicacid
• Formula: C22H36O3
• Molecular Weight: 348.52
• Purity: >97 %
• Description: Noncompetitive inhibitor of PCAF and p300 histone acetyltransferase (HAT) activity (IC 50 values are ~5.0 and ~8.5 μ M respectively). Inhibits NF- κ B activation. Also reported to selectively activate Aurora kinase A-mediated phosphorylation of histone H3. Exhibits antitumor, antimicrobial and antioxidant activity.

Product References

Small molecule modulators of histone acetyltransferase p300. - Small molecule modulators of histone acetyltransferase p300.

Balasubramanyam K, Swaminathan V, Ranganathan A, Kundu TK. J Biol Chem. 2003 May 23;278(21):19134-40. Epub 2003 Mar 6.

Specific small-molecule activator of Aurora kinase A induces autophosphorylation - Specific small-molecule activator of Aurora kinase A induces autophosphorylation

Kishore AH, Vedamurthy BM, Mantelingu K, Agrawal S, Reddy BA, Roy S, Rangappa KS, Kundu TK. J Med Chem. 2008 Feb 28;51(4):792-7.

Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone - Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone

Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M, Aggarwal BB. Blood. 2008 May 15;111(10):4880-91.