Anandamide

• Supplier: Tocris Bioscience
• Catalog: 2432
• Prices: $79.00, $295.00
• Sizes: 5 mg, 25 mg
• Function Type: Agonist
• Cas Number: 94421-68-8
• Chemical Name: N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
• Formula: C22H37NO2
• Molecular Weight: 347.54
• Description: Endogenous cannabinoid and TRPV1 receptor agonist (K i values are 89 and 371 nM at CB 1 and CB 2 receptors respectively; EC 50 values are 18, 31 and 27 nM at GPR55, CB 1 and CB 2 respectively; pK i = 5.68 for rTRPV1). Also blocks TNF- α -induced NF- κ B activation via direct inhibition of IKK. Also available in water soluble emulsion (Cat. No. 1017 ).

Product References

Isolation and structure of a brain constituent that binds to the cannabinoid - Isolation and structure of a brain constituent that binds to the cannabinoid

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Structure-activity relationship for the endogenous cannabinoid, anandamide, and - Structure-activity relationship for the endogenous cannabinoid, anandamide, and

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Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid - Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid

Sancho R, Calzado MA, Di Marzo V, Appendino G, Munoz E. Mol Pharmacol. 2003 Feb;63(2):429-38.

The orphan receptor GPR55 is a novel cannabinoid receptor. - The orphan receptor GPR55 is a novel cannabinoid receptor.

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