(±)-Anatoxin A fumarate

• Supplier: Tocris Bioscience
• Catalog: 3388
• Prices: $189.00
• Sizes: 1 mg
• Function Type: Agonist
• Cas Number: 1219922-30-1
• Chemical Name: (±)-2-Acetyl-9-azabicyclo[4.2.1]non-2-enefumarate
• Formula: C10H15NO.C4H4O4
• Molecular Weight: 281.31
• Purity: >96 %
• Description: A potent nicotinic agonist (K i values are 1.25 and 1840 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Stimulates [ 3 H]-dopamine release from rat striatal synaptosomes (EC 50 = 136 nM).

Product References

Induced release of acetylcholine from guinea pig ileum longitudinal - Induced release of acetylcholine from guinea pig ileum longitudinal

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Behavioural effects of anatoxin, a potent nicotinic agonist, in rats. - Behavioural effects of anatoxin, a potent nicotinic agonist, in rats.

Stolerman IP, Albuquerque EX, Garcha HS. Neuropharmacology. 1992 Mar;31(3):311-4.

(+)-Anatoxin-a is a potent agonist at neuronal nicotinic acetylcholine receptors. - (+)-Anatoxin-a is a potent agonist at neuronal nicotinic acetylcholine receptors.

Thomas P, Stephens M, Wilkie G, Amar M, Lunt GG, Whiting P, Gallagher T, Pereira E, Alkondon M, Albuquerque EX, et al.. J Neurochem. 1993 Jun;60(6):2308-11.

UB-165: a novel nicotinic agonist with subtype selectivity implicates the - UB-165: a novel nicotinic agonist with subtype selectivity implicates the

Sharples CG, Kaiser S, Soliakov L, Marks MJ, Collins AC, Washburn M, Wright E, Spencer JA, Gallagher T, Whiteaker P, Wonnacott S. J Neurosci. 2000 Apr 15;20(8):2783-91.