Andrographolide

Name Andrographolide
Supplier Tocris Bioscience
Catalog 0789
Prices $95.00
Sizes 50 mg
Function Type Inhibitor
Cas Number 5508-58-7
Chemical Name (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone
Formula C20H30O5
Molecular Weight 350.45
Purity >99 %
Description Inhibitor of NF- κ B signaling; also attenuates concanavaline-induced IFN γ production in murine T cells (IC 50 = 1.7 μ M). Blocks androgen receptor (AR) expression in AR-expressing C4-2 cells. Activates Nrf2 in BEAS-2B cells in response to cigarette smoke extract.
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