Ani 9

Name Ani 9
Supplier Tocris Bioscience
Catalog 1158
Prices $165.00, $695.00
Sizes 10 mg, 50 mg
Function Type Blocker
Cas Number 356102-14-2
Chemical Name 2-(4-Chloro-2-methylphenoxy)-N'-(2-methoxybenzylidene)acetohydrazide
Formula C17H17ClN2O3
Molecular Weight 332.78
Purity >98 %
Description Potent and selective TMEM16A (Anoctamin-1; ANO1) blocker (IC 50 = 77 nM). Displays no effect on ANO2 activity (at 10 μ M). Also exhibits no effect on intracellular calcium signaling or CFTR and ENaC channel activity (at 30 μ M).
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Product References

Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam. - Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam.

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Aniracetam reduces glutamate receptor desensitization and slows the decay of fast - Aniracetam reduces glutamate receptor desensitization and slows the decay of fast

Isaacson JS, Nicoll RA. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10936-40.

Anxiolytic effects of aniracetam in three different mouse models of anxiety and - Anxiolytic effects of aniracetam in three different mouse models of anxiety and

Nakamura K, Kurasawa M. Eur J Pharmacol. 2001 May 18;420(1):33-43.