D-AP4

Name D-AP4
Supplier Tocris Bioscience
Catalog 3699
Prices $225.00, $925.00
Sizes 10 mg, 50 mg
Function Type Antagonist
Cas Number 78739-01-2
Chemical Name D-(-)-2-Amino-4-phosphonobutyricacid
Formula C4H10NO5P
Molecular Weight 183.1
Purity >98 %
Description Broad spectrum excitatory amino acid receptor antagonist. Also agonist at the quisqualate-sensitized AP6 site in hippocampus where it is less potent than L-AP4. DL Mixture (Cat. No. 0101) and L-isomer (Cat. No. 0103) also available.
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Product References

Actions of D and L forms of 2-amino-5-phosphonovalerate and - Actions of D and L forms of 2-amino-5-phosphonovalerate and

Davies J, Watkins JC. Brain Res. 1982 Mar 11;235(2):378-86.

The effects of a series of omega-phosphonic alpha-carboxylic amino acids on - The effects of a series of omega-phosphonic alpha-carboxylic amino acids on

Evans RH, Francis AA, Jones AW, Smith DA, Watkins JC. Br J Pharmacol. 1982 Jan;75(1):65-75.

Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6) - Utilization of the resolved L-isomer of 2-amino-6-phosphonohexanoic acid (L-AP6)

Schulte MK, Roon RJ, Chalmers DJ, Sunter DC, Koerner JF. Brain Res. 1994 Jun 27;649(1-2):203-7.