Apcin

Name Apcin
Supplier Tocris Bioscience
Catalog 2511
Prices $149.00, $629.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 300815-04-7
Chemical Name 3-(2-Methyl-5-nitroimidazol-1-yl)-N-(2,2,2-trichloro-1-phenylaminoethyl)propionamide
Formula C13H14Cl3N7O4
Molecular Weight 438.65
Purity >98 %
Description Cdc20 inhibitor; inhibits Cdc20-substrate interaction. Blocks substrate-mediated Cdc20 loading onto the anaphase-promoting complex (APC). Inhibits APC-dependent ubiquitylation. Prolongs mitotic duration in RPE1 cells in combination with proTAME (prodrug of TAME (Cat.No. 4506)) in vitro .
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