Apelin-36 (human)

Name	Apelin-36 (human)
Supplier	Tocris Bioscience
Catalog	3007
Prices	$419.00
Sizes	1 mg
Function Type	Agonist
Cas Number	252642-12-9
Formula	C184H297N69O43S
Molecular Weight	4195.87
Description	Endogenous APJ receptor agonist (EC 50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC 50 = 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
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Product References

Apelin peptides block the entry of human immunodeficiency virus (HIV). - Apelin peptides block the entry of human immunodeficiency virus (HIV).

Zou MX, Liu HY, Haraguchi Y, Soda Y, Tatemoto K, Hoshino H. FEBS Lett. 2000 May 4;473(1):15-8.

Pharmacological and immunohistochemical characterization of the APJ receptor and - Pharmacological and immunohistochemical characterization of the APJ receptor and

Medhurst AD, Jennings CA, Robbins MJ, Davis RP, Ellis C, Winborn KY, Lawrie KW, Hervieu G, Riley G, Bolaky JE, Herrity NC, Murdock P, Darker JG. J Neurochem. 2003 Mar;84(5):1162-72.