Apocynin

• Supplier: Tocris Bioscience
• Catalog: 1227
• Prices: $45.00
• Sizes: 50 mg
• Function Type: Inhibitor
• Cas Number: 498-02-2
• Chemical Name: 4'-Hydroxy-3'-methoxyacetophenone
• Formula: C9H10O3
• Molecular Weight: 166.17
• Purity: >99 %
• Description: NADPH oxidase inhibitor. Demonstrates anti-inflammatory properties in a mouse model of carrageenan-induced pleurisy. Bioactivated by intracellular peroxidases; acts as an antioxidant in endothelial cells and vascular smooth muscle cells.

Product References

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by - Characteristics of the inhibition of NADPH oxidase activation in neutrophils by

Stolk J, Hiltermann TJ, Dijkman JH, Verhoeven AJ. Am J Respir Cell Mol Biol. 1994 Jul;11(1):95-102.

Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant. - Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

Heumuller S, Wind S, Barbosa-Sicard E, Schmidt HH, Busse R, Schroder K, Brandes RP. Hypertension. 2008 Feb;51(2):211-7. Epub 2007 Dec 17.

Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. - Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation.

Impellizzeri D, Esposito E, Mazzon E, Paterniti I, Di Paola R, Bramanti P, Cuzzocrea S. Biochem Pharmacol. 2011 Mar 1;81(5):636-48.