AR-C 66096 tetrasodium salt

• Supplier: Tocris Bioscience
• Catalog: 0928
• Prices: $319.00
• Sizes: 1 mg
• Function Type: Antagonist
• Cas Number: 145782-74-7
• Chemical Name: 2-(Propylthio)adenosine-5'-O-(β,γ-difluoromethylene)triphosphatetetrasodiumsalt
• Formula: C14H18F2N5Na4O12P3S
• Molecular Weight: 703.26
• Purity: >98 %
• Description: Potent and selective P2Y 12 receptor antagonist. Blocks ADP-induced inhibition of adenylyl cyclase in vitro (pK B =7.6) and inhibits ADP-induced aggregation of washed human platelets (pIC 50 = 8.16).

Product References

FPL 66096: a novel, highly potent and selective antagonist at human platelet - FPL 66096: a novel, highly potent and selective antagonist at human platelet

Humphries RG, Tomlinson W, Ingall AH, Cage PA, Leff P. Br J Pharmacol. 1994 Nov;113(3):1057-63.

Antagonists of the platelet P2T receptor: a novel approach to antithrombotic - Antagonists of the platelet P2T receptor: a novel approach to antithrombotic

Ingall AH, Dixon J, Bailey A, Coombs ME, Cox D, McInally JI, Hunt SF, Kindon ND, Teobald BJ, Willis PA, Humphries RG, Leff P, Clegg JA, Smith JA, Tomlinson W. J Med Chem. 1999 Jan 28;42(2):213-20.

Activity of adenosine diphosphates and triphosphates on a P2Y(T) -type receptor - Activity of adenosine diphosphates and triphosphates on a P2Y(T) -type receptor

Simon J, Vigne P, Eklund KM, Michel AD, Carruthers AM, Humphrey PP, Frelin C, Barnard EA. Br J Pharmacol. 2001 Jan;132(1):173-82.