Name | AR-M 1896 |
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Supplier | Tocris Bioscience |
Catalog | 4335 |
Prices | $255.00 |
Sizes | 1 mg |
Function Type | Agonist |
Cas Number | 367518-31-8 |
Formula | C54H81N13O14 |
Molecular Weight | 1136.31 |
Description | Selective galanin GAL 2 receptor agonist (IC 50 values are 1.76 and 879 nM for GAL 2 and GAL 1 respectively). Also shows moderate affinity for GAL 3 receptors (K i values are 88 and 271 nM for GAL 2 and GAL 3 respectively). Antiepileptogenic agent; prevents full seizures and postkindling increases in hippocampal excitability. |
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Lu X, Lundstrom L, Bartfai T. Neuropeptides. 2005 Jun;39(3):165-7. Epub 2005 Feb 1.
Mazarati A, Lundstrom L, Sollenberg U, Shin D, Langel U, Sankar R. J Pharmacol Exp Ther. 2006 Aug;318(2):700-8. Epub 2006 May 12.