Name | AS 252424 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 5430 |
Prices | $225.00 |
Sizes | 10 mg |
Function Type | Inhibitor |
Cas Number | 900515-16-4 |
Chemical Name | 5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione |
Formula | C14H8FNO4S |
Molecular Weight | 305.28 |
Purity | >98 % |
Description | Potent and selective inhibitor of PI 3-kinase γ (IC 50 values are 33 and 935 nM for PI 3-K γ and PI 3-K α respectively). |
Supplier Page | Shop |
Condliffe AM, Davidson K, Anderson KE, Ellson CD, Crabbe T, Okkenhaug K, Vanhaesebroeck B, Turner M, Webb L, Wymann MP, Hirsch E, Ruckle T, Camps M, Rommel C, Jackson SP, Chilvers ER, Stephens LR, Hawkins PT. Blood. 2005 Aug 15;106(4):1432-40. Epub 2005 May 5.
Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Francon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Ruckle T. J Med Chem. 2006 Jun 29;49(13):3857-71.