| Name | AS 605240 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3671 |
| Prices | $155.00, $645.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 648450-29-7 |
| Chemical Name | 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione |
| Formula | C12H7N3O2S |
| Molecular Weight | 257.27 |
| Purity | >98 % |
| Description | Potent and selective inhibitor of PI 3-kinase γ (PI 3-K γ ) (IC 50 = 8 nM). Displays 30-fold selectivity over PI 3-K δ and PI 3-K β and 7.5-fold selectivity over PI 3-K α . Suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. Orally active and ATP-competitive. |
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