Astressin

• Supplier: Tocris Bioscience
• Catalog: 3489
• Prices: $319.00
• Sizes: 500 µg
• Function Type: Antagonist
• Cas Number: 170809-51-5
• Formula: C161H269N49O42
• Molecular Weight: 3563.2
• Description: Potent corticotropin-releasing factor (CRF) receptor antagonist (K i values are 2, 1.5 and 1 nM at CRF 1 , CRF 2 α and CRF 2 β ). Reduces ACTH secretion, blocks delayed gastric emptying and is neuroprotective in vivo .

Product References

Potent, structurally constrained agonists and competitive antagonists of - Potent, structurally constrained agonists and competitive antagonists of

Gulyas J, Rivier C, Perrin M, Koerber SC, Sutton S, Corrigan A, Lahrichi SL, Craig AG, Vale W, Rivier J. Proc Natl Acad Sci U S A. 1995 Nov 7;92(23):10575-9.

Astressin, a novel and potent CRF antagonist, is neuroprotective in the - Astressin, a novel and potent CRF antagonist, is neuroprotective in the

Maecker H, Desai A, Dash R, Rivier J, Vale W, Sapolsky R. Brain Res. 1997 Jan 2;744(1):166-70.

Peripheral injection of a new corticotropin-releasing factor (CRF) antagonist, - Peripheral injection of a new corticotropin-releasing factor (CRF) antagonist,

Martinez V, Rivier J, Tache Y. J Pharmacol Exp Ther. 1999 Aug;290(2):629-34.

Corticotropin releasing factor receptors and their ligand family. - Corticotropin releasing factor receptors and their ligand family.

Perrin MH, Vale WW. Ann N Y Acad Sci. 1999 Oct 20;885:312-28.