Astressin 2B

• Supplier: Tocris Bioscience
• Catalog: 1606
• Prices: $389.00
• Sizes: 500 µg
• Function Type: Antagonist
• Cas Number: 681260-70-8
• Formula: C183H307N49O53
• Molecular Weight: 4041.69
• Description: Potent and selective corticotropin-releasing factor receptor 2 (CRF 2 ) antagonist (IC 50 values are 1.3 and > 500 nM for CRF 2 and CRF 1 respectively). Antagonizes CRF 2 -mediated inhibition of gastric emptying.

Product References

Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective - Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective

Rivier J, Gulyas J, Kirby D, Low W, Perrin MH, Kunitake K, DiGruccio M, Vaughan J, Reubi JC, Waser B, Koerber SC, Martinez V, Wang L, Tache Y, Vale W. J Med Chem. 2002 Oct 10;45(21):4737-47.

Peptide ligand binding properties of the corticotropin-releasing factor (CRF) - Peptide ligand binding properties of the corticotropin-releasing factor (CRF)

Hoare SR, Sullivan SK, Fan J, Khongsaly K, Grigoriadis DE. Peptides. 2005 Mar;26(3):457-70.

The effect of lateral septum corticotropin-releasing factor receptor 2 activation - The effect of lateral septum corticotropin-releasing factor receptor 2 activation

Henry B, Vale W, Markou A. J Neurosci. 2006 Sep 6;26(36):9142-52.