Name | AZD 1283 |
---|---|
Supplier | Tocris Bioscience |
Catalog | 4099 |
Prices | $135.00, $569.00 |
Sizes | 10 mg, 50 mg |
Function Type | Antagonist |
Cas Number | 919351-41-0 |
Chemical Name | Ethyl5-cyano-2-methyl-6-[4-[[[(phenylmethyl)sulfonyl]amino]carbonyl]-1-piperidinyl]-3-pyridinecarboxylate |
Formula | C23H26N4O5S |
Molecular Weight | 470.54 |
Purity | >98 % |
Description | High affinity P2Y 12 antagonist (K d = 11 nM). Causes a dose-dependent increase in blood flow and inhibits ADP-induced platelet aggregation in vivo . Antithrombotic. |
Supplier Page | Shop |
Ioannidis S, Lamb ML, Wang T, Almeida L, Block MH, Davies AM, Peng B, Su M, Zhang HJ, Hoffmann E, Rivard C, Green I, Howard T, Pollard H, Read J, Alimzhanov M, Bebernitz G, Bell K, Ye M, Huszar D, Zinda M. J Med Chem. 2011 Jan 13;54(1):262-76.
Xin H, Herrmann A, Reckamp K, Zhang W, Pal S, Hedvat M, Zhang C, Liang W, Scuto A, Weng S, Morosini D, Cao ZA, Zinda M, Figlin R, Huszar D, Jove R, Yu H. Cancer Res. 2011 Nov 1;71(21):6601-10.