| Name | AZD 5438 |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 4837 |
| Prices | $225.00, $925.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Inhibitor |
| Cas Number | 602306-29-6 |
| Chemical Name | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Formula | C18H21N5O2S |
| Molecular Weight | 371.46 |
| Purity | >99 % |
| Description | Potent inhibitor of cyclin-dependent kinase (cdk) 1, 2 and 9 (IC 50 values are 16, 6 and 20 nM respectively). Exhibits antiproliferative activity in human tumor cell lines. Blocks cell cycling at G 2 -M, S and G 1 phases; reduces the proportion of actively cycling cells in vivo . |
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