Azithromycin

• Supplier: Tocris Bioscience
• Catalog: 4553
• Prices: $109.00
• Sizes: 50 mg
• Cas Number: 83905-01-5
• Chemical Name: 13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
• Formula: C38H72N2O12
• Molecular Weight: 748.98
• Purity: >99 %
• Description: Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models.

Product References

Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new - Pharmacokinetic and in vivo studies with azithromycin (CP-62,993), a new

Girard AE, Girard D, English AR, Gootz TD, Cimochowski CR, Faiella JA, Haskell SL, Retsema JA. Antimicrob Agents Chemother. 1987 Dec;31(12):1948-54.

Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring - Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring

Retsema J, Girard A, Schelkly W, Manousos M, Anderson M, Bright G, Borovoy R, Brennan L, Mason R. Antimicrob Agents Chemother. 1987 Dec;31(12):1939-47.

Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilis - Macrolide antibiotics inhibit 50S ribosomal subunit assembly in Bacillus subtilis

Champney WS, Burdine R. Antimicrob Agents Chemother. 1995 Sep;39(9):2141-4.