Balicatib

Name Balicatib
Supplier Tocris Bioscience
Catalog 1761
Prices $149.00, $629.00
Sizes 10 mg, 50 mg
Function Type Inhibitor
Cas Number 354813-19-7
Chemical Name N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide
Formula C23H33N5O2
Molecular Weight 411.54
Purity >98 %
Description Potent and selective cathepsin K inhibitor (IC 50 values are 1.4, 56 and 480 nM for human, rat and mouse cathepsin K, respectively). Exhibits >300-fold selectivity for cathepsin K over cathepsins L, B and S. Long term supratherapeutic dosing increases tissue levels of cathepsins L and B in rats.
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