BAPTA AM

• Supplier: Tocris Bioscience
• Catalog: 2786
• Prices: $139.00
• Sizes: 25 mg
• Cas Number: 126150-97-8
• Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraaceticacidtetrakis(acetoxymethylester)
• Formula: C34H40N2O18
• Molecular Weight: 764.68
• Purity: >95 %
• Description: Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hK v 1.5, hK V 11.1 (hERG) and hK v 1.3 channels (K i values are 1.23, 1.30 and 1.45 μ M respectively). Displays antithrombotic activity in vitro .

Product References

Enhanced release of prostacyclin from quin 2-loaded endothelial cells. - Enhanced release of prostacyclin from quin 2-loaded endothelial cells.

Raspe E, Ramboer I, Galand N, Boeynaems JM. Eur J Pharmacol. 1989 Apr 25;163(2-3):345-51.

The membrane permeable calcium chelator BAPTA-AM directly blocks human ether - The membrane permeable calcium chelator BAPTA-AM directly blocks human ether

Tang Q, Jin MW, Xiang JZ, Dong MQ, Sun HY, Lau CP, Li GR. Biochem Pharmacol. 2007 Dec 3;74(11):1596-607. Epub 2007 Aug 3.