BAY 299

• Supplier: Tocris Bioscience
• Catalog: 1744
• Prices: $139.00, $585.00
• Sizes: 10 mg, 50 mg
• Function Type: Inhibitor
• Chemical Name: 6-(3-Hydroxypropyl)-2-(1,3,6-trimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
• Formula: C25H23N3O4
• Molecular Weight: 429.47
• Purity: >98 %
• Description: Potent and selective BRD1 and TAF1 inhibitor (IC 50 values are 6 and 13 nM, respectively). Displays selectivity over other bromodomains (>30-fold over other members of the BRPF family; BRD9 and ATAD2; >300-fold over BRD4). Displays BRD1 and TAF1 inhibition in a NanoBRET cell assay.

Product References

BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse - BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse

Carroll FY, Stolle A, Beart PM, Voerste A, Brabet I, Mauler F, Joly C, Antonicek H, Bockaert J, Muller T, Pin JP, Prezeau L. Mol Pharmacol. 2001 May;59(5):965-73.

Neuroprotective and behavioral effects of the selective metabotropic glutamate - Neuroprotective and behavioral effects of the selective metabotropic glutamate

De Vry J, Horvath E, Schreiber R. Eur J Pharmacol. 2001 Oct 5;428(2):203-14.

Involvement of the mGluR1 receptor in hippocampal synaptic plasticity and - Involvement of the mGluR1 receptor in hippocampal synaptic plasticity and

Gil-Sanz C, Delgado-Garcia JM, Fairen A, Gruart A. Cereb Cortex. 2008 Jul;18(7):1653-63. Epub 2007 Nov 17.