( R )-(+)-Bay K 8644

• Supplier: Tocris Bioscience
• Catalog: 1544
• Prices: $255.00, $1,045.00
• Sizes: 10 mg, 50 mg
• Function Type: Blocker
• Cas Number: 98791-67-4
• Chemical Name: (4R)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-trifluoromethyl)phenyl]-3-pyridinecarboxylicacidmethylester
• Formula: C16H15F3N2O4
• Molecular Weight: 356.3
• Purity: >97 %
• Description: L-type Ca 2+ -channel blocker with negative inotropic and vasodilatatory effects in vivo . Enantiomer showing opposite effects to the racemate (±)-Bay K 8644 (Cat. No. 1544) and (S)-(-)- enantiomer (Cat. No. 1546).

Product References

The optical isomers of the 1,4-dihydropyridine BAY K 8644 show opposite effects - The optical isomers of the 1,4-dihydropyridine BAY K 8644 show opposite effects

Franckowiak G, Bechem M, Schramm M, Thomas G. Eur J Pharmacol. 1985 Aug 15;114(2):223-6.

Enantiomer selectivity and the development of tolerance to the behavioral effects - Enantiomer selectivity and the development of tolerance to the behavioral effects

O'Neill SK, Bolger GT. Brain Res Bull. 1988 Dec;21(6):865-72.

Opposite cardiac actions of the enantiomers of Bay K 8644 at different membrane - Opposite cardiac actions of the enantiomers of Bay K 8644 at different membrane

Ravens U, Schopper HP. Naunyn Schmiedebergs Arch Pharmacol. 1990 Mar;341(3):232-9.

Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and - Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and

Shi Y, Desponts C, Do JT, Hahm HS, Scholer HR, Ding S. Cell Stem Cell. 2008 Nov 6;3(5):568-74.