BAY-u 9773

• Supplier: Tocris Bioscience
• Catalog: 2732
• Prices: $165.00
• Sizes: 50 µg
• Function Type: Antagonist
• Cas Number: 154978-38-8
• Chemical Name: 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoicacid
• Formula: C27H36O5S
• Molecular Weight: 472.64
• Description: Cysteinyl leukotriene receptor antagonist with equal affinity at both CysLT 1 and CysLT 2 receptors (pK B values are 6.8 and 6.5 respectively). Competitive antagonist of LTC 4 - and LTE 4 -induced contractions of the guinea pig trachea.

Product References

A second cysteinyl leukotriene receptor in human lung. - A second cysteinyl leukotriene receptor in human lung.

Labat C, Ortiz JL, Norel X, Gorenne I, Verley J, Abram TS, Cuthbert NJ, Tudhope SR, Norman P, Gardiner P, et al.. J Pharmacol Exp Ther. 1992 Nov;263(2):800-5.

Cysteinyl leukotriene receptors in the human lung: what's new? - Cysteinyl leukotriene receptors in the human lung: what's new?

Gorenne I, Norel X, Brink C. Trends Pharmacol Sci. 1996 Oct;17(10):342-5.

Functional characteristics of cysteinyl-leukotriene receptor subtypes. - Functional characteristics of cysteinyl-leukotriene receptor subtypes.

Back M. Life Sci. 2002 Jun 28;71(6):611-22.