Name | Bazedoxifene acetate |
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Supplier | Tocris Bioscience |
Catalog | 5266 |
Prices | $189.00, $765.00 |
Sizes | 10 mg, 50 mg |
Function Type | Modulator |
Cas Number | 198481-33-3 |
Chemical Name | 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-olacetate |
Formula | C30H34N2O3.C2H4O2 |
Molecular Weight | 530.65 |
Purity | >98 % |
Description | Potent selective estrogen receptor modulator (SERM) (IC 50 values are 26 and 99 nM for ER α and ER β respectively). Inhibits 17 β -estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium. |
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