Bepridil hydrochloride

Name Bepridil hydrochloride
Supplier Tocris Bioscience
Catalog 0754
Prices $95.00
Sizes 50 mg
Function Type Blocker
Cas Number 68099-86-5
Chemical Name N-Benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)anilinehydrochloride
Formula C24H34N2O.HCl
Molecular Weight 403
Purity >99 %
Description Calcium channel blocker. Also inhibits Na + /Ca 2+ exchange (NCX), sodium channels and cardiac sarcolemmal K ATP channels; opens mitochondrial K ATP channels. Antiarrhythmic and antihypertensive; acts as a calcium sensitizer.
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Product References

Bepridil block of cardiac calcium and sodium channels. - Bepridil block of cardiac calcium and sodium channels.

Yatani A, Brown AM, Schwartz A. J Pharmacol Exp Ther. 1986 Apr;237(1):9-17.

Pharmacology of bepridil. - Pharmacology of bepridil.

Gill A, Flaim SF, Damiano BP, Sit SP, Brannan MD. Am J Cardiol. 1992 Apr 9;69(11):11D-16D.

Blocking effect of bepridil on Na+/Ca2+ exchange current in guinea pig cardiac - Blocking effect of bepridil on Na+/Ca2+ exchange current in guinea pig cardiac

Watanabe Y, Kimura J. Jpn J Pharmacol. 2001 Apr;85(4):370-5.

Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks - Bepridil, an antiarrhythmic drug, opens mitochondrial KATP channels, blocks

Sato T, Costa AD, Saito T, Ogura T, Ishida H, Garlid KD, Nakaya H. J Pharmacol Exp Ther. 2006 Jan;316(1):182-8. Epub 2005 Sep 20.