Betulinic acid

• Supplier: Tocris Bioscience
• Catalog: 4778
• Prices: $75.00, $285.00
• Sizes: 10 mg, 50 mg
• Cas Number: 472-15-1
• Chemical Name: (+)-(3β)-3-Hydroxylup-20(29)-en-28-oicacid
• Formula: C30H48O3
• Molecular Weight: 456.7
• Description: Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species (ROS) and activates NF- κ B. Also a GPBA receptor partial agonist (EC 50 = 1.04 μ M, efficacy 83%).

Product References

Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents. - Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents.

Kashiwada Y, Hashimoto F, Cosentino LM, Chen CH, Garrett PE, Lee KH. J Med Chem. 1996 Mar 1;39(5):1016-7.

Betulinic Acid for cancer treatment and prevention. - Betulinic Acid for cancer treatment and prevention.

Fulda S. Int J Mol Sci. 2008 Jun;9(6):1096-107.

Structure-activity relationship study of betulinic acid, a novel and selective - Structure-activity relationship study of betulinic acid, a novel and selective

Genet C, Strehle A, Schmidt C, Boudjelal G, Lobstein A, Schoonjans K, Souchet M, Auwerx J, Saladin R, Wagner A. J Med Chem. 2010 Jan 14;53(1):178-90.