| Name | Bexarotene |
|---|---|
| Supplier | Tocris Bioscience |
| Catalog | 3906 |
| Prices | $75.00, $315.00 |
| Sizes | 10 mg, 50 mg |
| Function Type | Agonist |
| Cas Number | 153559-49-0 |
| Chemical Name | 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoicacid |
| Formula | C24H28O2 |
| Molecular Weight | 348.48 |
| Purity | >99 % |
| Description | Potent and selective RXR agonist (EC 50 values are 24, 25 and 33 nM for RXR β , RXR γ and RXR α , respectively). Exhibits >300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro , and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts. |
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