2-BFI hydrochloride

Name 2-BFI hydrochloride
Supplier Tocris Bioscience
Catalog 3743
Prices $139.00, $585.00
Sizes 10 mg, 50 mg
Cas Number 89196-95-2
Chemical Name 2-(2-Benzofuranyl)-2-imidazolinehydrochloride
Formula C11H10N2O.HCl
Molecular Weight 222.67
Description High affinity I 2 ligand (K i = 9.8 nM). Putative I 2 agonist; potentiates morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.
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Product References

Labelling of I2B-imidazoline receptors by [3H]2-(2-benzofuranyl)-2-imidazoline - Labelling of I2B-imidazoline receptors by [3H]2-(2-benzofuranyl)-2-imidazoline

Alemany R, Olmos G, Garcia-Sevilla JA. Naunyn Schmiedebergs Arch Pharmacol. 1997 Jul;356(1):39-47.

Activation of I(2)-imidazoline receptors enhances supraspinal morphine analgesia - Activation of I(2)-imidazoline receptors enhances supraspinal morphine analgesia

Sanchez-Blazquez P, Boronat MA, Olmos G, Garcia-Sevilla JA, Garzon J. Br J Pharmacol. 2000 May;130(1):146-52.

Locomotor effects of imidazoline I2-site-specific ligands and monoamine oxidase - Locomotor effects of imidazoline I2-site-specific ligands and monoamine oxidase

Macinnes N, Duty S. Br J Pharmacol. 2004 Dec;143(8):952-9. Epub 2004 Nov 15.