Name | rac BHFF |
---|---|
Supplier | Tocris Bioscience |
Catalog | 3326 |
Prices | $139.00, $585.00 |
Sizes | 10 mg, 50 mg |
Function Type | Modulator |
Cas Number | 123557-91-5 |
Chemical Name | 5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone |
Formula | C17H21F3O3 |
Molecular Weight | 330.34 |
Purity | >98 % |
Description | Potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). Exhibits anxiolytic activity in vivo and is orally active. |
Supplier Page | Shop |
Malherbe P, Masciadri R, Norcross RD, Knoflach F, Kratzeisen C, Zenner MT, Kolb Y, Marcuz A, Huwyler J, Nakagawa T, Porter RH, Thomas AW, Wettstein JG, Sleight AJ, Spooren W, Prinssen EP. Br J Pharmacol. 2008 Jun;154(4):797-811.
Koek W, Cheng K, Rice KC. J Pharmacol Exp Ther. 2013 Mar;344(3):553-60.